![]() ![]() This change in behavior is known as meth addiction, or methamphetamine use disorder. The drug also makes dramatic changes to your brain structure in a very short time, which can lead you to keep using it despite any negative consequences on your life, health, and relationships. It sends your brain’s dopamine levels into the stratosphere, so to speak. Meth produces more reward chemicals than your brain can fully handle. If you take more than one stimulant at a time, you have a higher risk of experiencing a stroke or heart attack, and your body may overheat. It’s also dangerous to combine meth with other stimulants, like cocaine. These rapid changes can put a lot of strain on your body, to the point where you need emergency medical attention. What’s more, combining meth - a stimulant - with depressants like alcohol, opioids, or benzodiazepines can have a tug-of-war effect on your bodily functions.įor instance, your heart rate may speed up, slow down, and then speed up again, because your body metabolizes each drug at different rates. You may not feel alcohol’s effects as you typically would, so you might drink more alcohol than your body can process. ![]() But it may also lead you to feel more anxious and agitated - not to mention increase your risk of alcohol poisoning or overdose. But it’s not a good idea to mix these substances.Īlcohol could potentially boost the effects of meth by heightening its euphoric effects. If you feel calmer when drinking alcohol, you might assume it’ll help you feel less restless or jittery when you take meth. Protection of personal information - Laboratory Medicine comply with the Trust Data Protection policy and have procedures in place to allow the Directorate and its employees to comply with the Data Protection act 1998 and associated best practice and guidance.Does it interact with alcohol and other drugs? However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.įor further test information, please visit the test database. Tests not appearing on the UKAS Schedule of Accreditation currently remain outside of our scope of accreditation. ![]() United Kingdom Health Security Agency laboratory is a UKAS accredited medical laboratory No.8213.Heartlands, Good Hope and Solihull Hospital pathology laboratories are a UKAS accredited medical laboratory No.8217.For a list of accredited tests and other information please visit the UKAS website using the following link: The laboratories at Heartlands Hospital, Good Hope Hospital and Solihull Hospital form part of the services provided by University Hospitals Birmingham and are UKAS (United Kingdom Accreditation Service) accredited to the ISO 15189:2012 standard. Stimulant use (including MDMA, MDA, MDEA, amfetamine, methamfetamine, 4MEC, MDPV, MMC & BZP) may also be detected via our urinary Drugs of Abuse Screen by LC-MS/MS. Please note, this assay is for the quantitative determination of amfetamine in blood. Myocardial infarction, aortic dissection, ischaemic stroke and cerebral haemorrhage have been described in users of the drug. Chronic useage is associated with a high incidence of weight loss, hallucinations and paranoid psychosis. Around 30% of amfetamine is excreted unchanged in urine, but this may increase to 74% in acid urine and decrease to 1% in alkaline urine.Įxcessive doses of amfetamine can cause restlessness, anxiety, confusion, irritability, hyperactivity and aggressive or bizarre behavior. These latter three metabolites are pharmacologically active and may contribute to the effects of the drug, especially in chronic usage. However, a small amount is converted by oxidation to norephedrine, and this compound and its parent are p-hydroxylated. It is also a metabolite of a number of other drugs including fenethylline, fenproporex and methamfetamine.Īmfetamine is largely inactivated during metabolism, being deaminated to phenyacetone, which is subsequently oxidized to benzoic acid and excreted as conjugates. Amfetamine is frequently abused for its stimulant effects and may be self-administered either orally or by intravenous injection in amounts of up to 2000 mg daily by tolerant addicts. The compound was first synthesized in 1887 and has been used since 1935 in the treatment of obesity, narcolepsy and hypotension. Amfetamine (Amphetamine) is a sympathomimetic phenethylamine derivative with prominent central stimulant activity. ![]()
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